Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 7, 1983 - Issue 1
4
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Erythroleukemia Manifesting δβ-Thalassemia

, , &
Pages 71-78 | Received 19 Oct 1982, Accepted 09 Dec 1982, Published online: 07 Jul 2009
 

Abstract

A 27 year old male with aplastic anemia developed a high fetal hemoglobin, a low hemoglobin A2, a decreased β/α synthetic ratio, and an increased G γ/A γ synthetic ratio. This acquired hemoglobinopathy resembling δβ-thalassemia was recognized at the onset of acute erythroleukemia. Certain features of this abnormal globin synthetic pattern resemble those of the normal fetus and thus appear to provide another example of gene expression by malignant cells resembling that of an earlier stage of the organism's development.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.