HB Sabine or α²β² 91 (F7)LEU→PRO in a Yugoslavian Boy

Abstract

Recently we had the opportunity t o study blood samples from a 7-year-old boy who was a patient a t the Institute of Maternal and Child Care in Beograd, Yugoslavia. The child was admitted because of a rather moderate anemia with pallor and a subicteric condition. He was splenectomized after a severe aplastic crisis. Hematological data obtained from him before and after splenectomy and from both parents are given in Table I. A persistent reticulocytosis was present in the patient. Many red cells showed distinct basophilic stippling and inclusion bodies could be observed in more than half of his erythrocytes.