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Hemoglobin
international journal for hemoglobin research
Volume 7, 1983 - Issue 3
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Miscellaneous Article

A Case of Hemoglobin Iwata [α87(F8)HIS → ARG] in China

Liu Guo-Yang Department of Medical Genetics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
,
Zhang Guei-Xiang Department of Medical Genetics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
,
Nie Shun-Yi Department of Medical Genetics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
,
Luo Hui-Yuan Department of Medical Genetics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
,
Teng Yu-Qin Department of Biochemistry, Medical College of Inner Mongolia Huhehot, People's Republic of China
,
Liu Shu-Ping Department of Biochemistry, Medical College of Inner Mongolia Huhehot, People's Republic of China
,
Song Min Department of Biochemistry, Medical College of Inner Mongolia Huhehot, People's Republic of China
,
Son Lin Department of Biochemistry, Medical College of Inner Mongolia Huhehot, People's Republic of China
,
Chen Song-Sen Department of Biochemistry and Molecular Eiology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
,
Jia Pei-Chen Department of Biochemistry and Molecular Eiology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
&
Liang Chih-Chuan Department of Biochemistry and Molecular Eiology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, People's Republic of China
 show all
Pages 279-282 | Received 17 Jan 1983, Accepted 22 May 1983, Published online: 07 Jul 2009
 
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Abstract

Hemoglobin Iwata was discovered in Japan in 1980 (1). Recently, we detected a slow-moving α-chain variant by cellulose acetate electrophoresis (2) in a family of the Han ethnic group during a survey carried out among students in Huhehot, Inner Mongolia. Structural analyses of the abnormal hemoglobin (Hb) demonstrated that it was Hb Iwata [α87 (F8) His→Arg]. This is the first example of this variant to be found in China.

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