Hemoglobinopathies in the Los Angeles Area

Abstract

Several surveys of abnormal hemoglobins in Los Angeles and in the Southwestern United States have been published in recent years (1–4), and the frequencies of the well known abnormal hemoglobins, such as Hbs S, C, and E, have been reported in this area; some rarer mutants and several new variants have also been described. In one study, an unselected population was studied by screening cord blood specimens in a large municipal hospital, and frequencies of Hbs S, C, and D were determined in various ethnic groups (3).