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Hemoglobin
international journal for hemoglobin research
Volume 10, 1986 - Issue 1
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Original Article

Interaction of Hemoglobin Siriraj with Hemoglobin S: A Mild Sickle Cell Syndrome

M. D. Rhoda INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
,
N. Arous INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
,
M. C. Garel INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
,
M. Mazarin Centre de Transfusion, Fort de France, 97200, Martinique, France
,
N. Monplaisir Centre de Transfusion, Fort de France, 97200, Martinique, France
,
F. Braconnier INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
,
J. Rosa INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
,
M. Cohen-solal INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
&
F. Galacteros INSERM Unite 91, Hopital Henri Mondor 94010 Creteil, France
 show all
Pages 21-31 | Received 16 Jul 1985, Accepted 04 Nov 1965, Published online: 07 Jul 2009
 
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Abstract

Hb Siriraj is a β chain variant in which β7 (A4) Glu is replaced by a lysine. It has been encountered in association with Hb S in a black man from Martinique. Some properties of Hb Siriraj are compared, particularly, with Hb C [α2β26(A3)Glu→Lys], and a study of its in vitro interaction with Hb S is discussed.

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