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Hemoglobin
international journal for hemoglobin research
Volume 12, 1988 - Issue 5-6
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Original Article

Thalassemia in the Silk Road Region of China

F. Qin Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
H. J. Li Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
L. Li Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
H. W. Li Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
X. S. Zhang Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
J. H. Yi Laboratory of Medical Genetics, Western Region Hospital, Urumqi, PR China
,
X. N. Zhao Second Sanatorium of PLA in Lintong, Xian, PR China
,
C. T. Zhang Second Sanatorium of PLA in Lintong, Xian, PR China
,
Z. M. Li Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
,
F. L. Xing Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
,
Y. Z. Wang Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
,
W. S. Zhang Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
,
K. X. Liang Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
&
W. Z. Ning Hemoglobin Study Group of the Lanzhou Military Area, Xinjiang, PR China
 show all
Pages 629-635 | Received 26 Jan 1988, Accepted 01 Jun 1988, Published online: 07 Jul 2009
 
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Abstract

This paper summarizes data obtained during a screening program involving 11,563 persons from the Silk Road region in China. The mean incidence of thalassemia is 1.62% with an increase from east to west. The incidence in the Hui population (3.01%) is higher than in Kazaks (2.92%), and in Uygur (2.22%). The Han population also has a higher incidence (0.98%) than seen for other regions in Northern China. The thalassemias observed are classified into seven groups; β-thalassemia accounts for 89.48% of the total, and α-thalassemia for 10.52%.

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