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Hemoglobin
international journal for hemoglobin research
Volume 12, 1988 - Issue 2
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Original Article

Thai (δβ)°-Thalassemia and its Lnteraction with γ-Thalassemia

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Pages 101-114 | Received 18 Aug 1987, Accepted 03 Feb 1988, Published online: 07 Jul 2009
 

Abstract

A variant of Southern Italian (δβ)° -thalassemia is described in a woman of Thai origin. The 3′ breakpoint in Thai (δβ)°-thalas-semia is located about 1 kb upstream to that in Southern Italian (δβ)°-thalassemia and produces a smaller deletion of ≊ 12.5 kb. Hematological phenotype, particularly Hb F output, is similar to that found in GγAγ(δβ)°-thalassemia despite the presence of a coexistent γ-thalassemia effect.

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