Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 36, 2012 - Issue 2
142
Views
4
CrossRef citations to date
0
Altmetric
Short Communications

Cord Blood Analysis for Rapid Prenatal Confirmation of Hb Bart’s Disease Using the Sebia Capillary Electrophoresis System

, , , &
Pages 186-191 | Received 30 May 2011, Accepted 03 Aug 2011, Published online: 22 Dec 2011
 

Abstract

Prenatal diagnosis of severe α-thalassemia (α-thal) diseases is usually performed by DNA analysis. To establish a simple and rapid method, we evaluated the reliability of cord blood hemoglobin (Hb) analysis using an automated capillary electrophoresis (CE) system. Our results demonstrated that analysis of fetal Hb using the Sebia CapillaryS 2 is an effective, accurate and simple alternative for prenatal diagnosis of Hb Bart’s (γ4) disease.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.