First Report of Acute Lymphoblastic Leukemia in an Egyptian Child with β-Thalassemia Major

Abstract

β-Thalassemia (β-thal) is the most common hereditary anemia in humans. With improvement of treatment protocols, patients are living longer and new complications have emerged. Few articles have reported the occurrence of malignancies among patients with β-thal in different parts of the world. We herein report the first pediatric patient with β-thal major (β-TM), who developed acute lymphoblastic leukemia in Egypt with analysis of the different theories of pathogenesis.

• Acute lymphoblastic leukemia (ALL)
• β-thalassemia (β-thal)
• children
• Egypt

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.