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Abstract
Hb Turriff is a new hemoglobin variant which we have identified in a diabetic individual. During the determination of Hb A by high performance liquid chromatography, an inappropriately elevated result was found to be due to the abnormal hemoglobin chromatographing with the Hb A1c fraction. This new hemoglobin variant, Hb Turriff [α99(66)Lys→Glu), is not associated with any hematological disturbance, and family investigations indicate that it has arisen as a de novo mutation.