Abstract
Hb G-Waimanalo or α64(E13)Asp→Asn was first discovered in 1973 in a male of Filipino ancestry (l), and later reported in Japanese and Filipino families (2–5). The same mutation was also detected in a family of Arabian origin as Hb Aida (6). It is a slow-moving variant in electrophoresis at alkaline pH, and cathodal in isoelectrofocusing (IEF) (3), which has been shown to be synthesized at a normal rate, to be stable in the isopropanol test, and to have a normal oxygen affinity (2,3). In this paper we describe the occurrence of the variant in a Caucasian family.