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Hemoglobin
international journal for hemoglobin research
Volume 22, 1998 - Issue 1
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Original Article

HB Silver Springs [β131(H9)GLNHIS], A New Hemoglobin Variant Found in Six African-Americans

, , , , &
Pages 37-44 | Received 06 May 1997, Accepted 16 Oct 1997, Published online: 07 Jul 2009
 

Abstract

We report a new hemoglobin variant which we have named Hb Silver Springs. This variant results from a substitution CAGĆC (GlnHis) at codon 131 of the β chain. It was detected only by cation exchange high performance liquid chromatography. This is the fifth reported substitution at codon 131. This variant does not appear to have any clinical or hematologic manifestations.

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