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Drug Development Communications Volume 2, 1976 - Issue 4-5
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Research Article

Potential use of Liquid Membranes for Emergency Treatment of Drug Overdose

John W. Frankenfeld Exxon Research and Engineering Company, P.O. Box 8, Linden, New Jersey, 07036
,
George C. Fuller Department of Pharmacology and Toxicology, University of Rhode Island, Kingston, Rhode Island, 02881
&
Christopher T. Rhodes Department of Pharmacy, University of Rhode Island, Kingston, Rhode Island, 02881
Pages 405-419 | Published online: 20 Oct 2008
 
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Abstract

Several liquid membrane formulations were evaluated for the absorption of model drugs from two different donor solutions. Up to 95% of both phenobarbital and aspirin (acetylsalicylic acid) were removed from pH 2 donors and more than 85% of the former from a pH 7 donor in

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