The Effect of Selected Nonionic and Anionic Gum Dispersions on the Effective Dialysis Rate and Urinary Excretion Rate of Salicylate

Maria O. Bachynsky Department of Allied Health & Industrial Sciences of the College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, 11439

Andrew J. Bartilucci Department of Allied Health & Industrial Sciences of the College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, 11439

Henry Eisen Department of Allied Health & Industrial Sciences of the College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, 11439

Charles I Jarowski Hoffmann La Roche, Inc., Nutley, New Jersey, 07110

Abstract

Comparably viscous noaionic and anionic gum dispersions were found to vary in their effect on salicylate dialysis through a semipermeable membrane. The urinary recovery rate of unchangea salicylate was affected by the coadministration of gums. Methylcellulose 4000 lowered the rate of excretion whereas sodium carboxymethylcellulose increased the rate.

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The Effect of Selected Nonionic and Anionic Gum Dispersions on the Effective Dialysis Rate and Urinary Excretion Rate of Salicylate

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The Effect of Selected Nonionic and Anionic Gum Dispersions on the Effective Dialysis Rate and Urinary Excretion Rate of Salicylate

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