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Research Article

Influence of Uric Acid on Photostability of Fd& C Blue no. 2

Pages 563-586 | Published online: 20 Oct 2008
 

Abstract

The effect of uric acid as a photoprotective agent for various solutions of FD&C Blue No. 2 was investivated. Due to the poor aqueous solubility of uric acid, solutions were made in glycerin, triethanolamine and N/5 NaOH. Uric acid in glycerin or triethanolamine was found to enhance the photostability of the dye solutions. The higher the concentration of uric acid in triethanolamine, the greater was the photoprotective action of uric acid. Increasing the amount of glycerin in solution resulted in acceleration of the rate of fading of the color presumably due to dielectric constant effect. The photoprotective action of uric acid was found to be influenced by the pH of the medium and its buffer species.

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