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Research Article

Dissolution of Some Lithium Dosage Forms and Correlation with Enslin Number

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Pages 147-167 | Published online: 20 Oct 2008
 

Abstract

The biopharmaceutic parameters of six conventional and one sustained release lithium carbonate commercial products were determined. From the dissolution data mean residence time, dissolution rate constants, and percent dissolved at 5 and 10 minutes were obtained. The ENSLIN numbers were compared with mean residence time and percent dissolved at 5 and 10 minutes. A good correlation was obtained between ENSLIN number and mean residence time for the conventional preparations.

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