![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
The friability and dissolution rate of various directly compressed phenobarbital formulations with microcrystalline cellulose as excipient are closely correlated with the compression force used in punching the tablets. Compliance with tolerance limits set for such technological characteristics can therefore be ensured by suitable control of compression force.