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Drug Development and Industrial Pharmacy Volume 13, 1987 - Issue 7
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Research Article

New Approach to Aqueous Granulation of Highly Hydrosoluble Drugs

J. L. Fábregas Research Institute Laboratorios Almirall, SA Barcelona, 08024, Spain
&
J. Cucala Research Institute Laboratorios Almirall, SA Barcelona, 08024, Spain
Pages 1217-1227 | Published online: 20 Oct 2008
 
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Abstract

The critical effect of binding solvents in aqueous wet granulation,on the physicalstability of tablets was investigated. The implications of the shelfcementation process in aqueous granulation of Piracetam are discussed.

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