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Abstract
The most recent dispersible enteric polymers such as AQUATERIC, HPMCP HP 55 F, EUDRAGIT L 100 55 and cellulose acetate phthalate (micronized in our laboratory), were evaluated on two different physical and chemical substrates (soluble and insoluble). Four standard formulations were used with and without the most common solid additives such as talc and titanium dioxide.
A good distribution of all coatings was obtained on the both substrates previously studied.
The mechanical properties and the dissolution profile of gastric resistance showed clearly that the methacrylic copolymer-based product is a good alternative to esther celluloses manufactured with the most modern technologies.