Evaluation of maltodextrin as binding agent

Abstract

Different types of maltodextrin were evaluated as binding agents in wet granulation process. Maltodextrins were added during wet granulation process in the dry form or as a solution. The granulation was performed in a planetary and a high shear mixer. Lactose monohydrate and dicalcium phosphate dihydrate were used as bulk materials. This study showed no difference in binding capacity between the different types of maltodextrin. Maltodextrins did not show any advantage as binding agent in comparison to native starch.