A Method for Quantitative Evaluation of the Effectiveness of tee Lubricants Used in Tablet Technology

A. Delacourte Laboratoire de Pharmacotechnie Industrielle Faculté de Pharmacie de, Lille, (France)

P. Predella Istituto di Technica Farmaceutica Facoltà di Farmacia di, Parma, (Italy)

P. Leterme Laboratoire de Pharmacotechnie Industrielle Faculté de Pharmacie de, Lille, (France)

D. Provasi Istituto di Technica Farmaceutica Facoltà di Farmacia di, Parma, (Italy)

P. Colombo Istituto di Technica Farmaceutica Facoltà di Farmacia di, Parma, (Italy)

U. Conte Dipartimento di Chimica Farmaceutica Facoltà di Farmacia di, Pavia, (Italy)

P. L. Catellani Istituto di Technica Farmaceutica Facoltà di Farmacia di, Parma, (Italy)

J. C. Guyot Laboratoire de Pharmacotechnie Industrielle Faculté de Pharmacie de, Lille, (France)

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Abstract

Modern formulation bases the appropriate selection of excipients on technological determinations. Due to negative effects on mechanical and biopharmaceutical properties of tablets, the amount of lubricant to be used requires optimization. Lubricants are difficult to evaluate in terms of effectiveness. The number of references existing in literature on this topic substantiates the necessity still remaining in pharmaceutics for lubricant testing (1, 2, 3, 4, 5).

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A Method for Quantitative Evaluation of the Effectiveness of tee Lubricants Used in Tablet Technology

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A Method for Quantitative Evaluation of the Effectiveness of tee Lubricants Used in Tablet Technology

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