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Drug Development and Industrial Pharmacy Volume 20, 1994 - Issue 4
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Research Article

Liposomes as Carriers for Drugs and Antigens: Approaches to Preserve Their Long Term Stability

Daan J.A. Crommelin Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, P.O. Box 80.082 TB, Utrecht, The Netherlands
,
Mustafa Grit Kao Corporation, Institute for Fundamental Research, 2606 Akabane, Haga-gun, Ichikai-machi, 321-34, Tochigi, Japan
,
Herre Talsma Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, P.O. Box 80.082 TB, Utrecht, The Netherlands
&
Nicolaas Jan Zuidam Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, P.O. Box 80.082 TB, Utrecht, The Netherlands
Pages 547-556 | Published online: 20 Oct 2008
 
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Abstract

Liposomes can be used for several different reasons in therapy. In this brief review the sources of chemical and physical instability of liposomes and the approaches for long term stabilization will be discussed.

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