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Abstract
Sheabutter is an abundant raw material in certain West African countries, but its low melting point for a tropical climate and the variability of its chemical composition, due to its extraction method, limit its use.
However this work has permitted to realize lipophile bases from sheabutter, with satisfactory pharmacotechnical characteristics (melting point, consistence, heat stability) according to the following procedure
_ Comparison of Burkina Faso sheabutter(BB) physicochemical properties with those of a purified sheabutter, Cetiol SB 45* (CT).
_ Formulation and control of lipophilic ointments
_ Evaluation of griseofulvin availability, widely used in Burkina Faso. from different formulations.
The appropriate choice of auxiliary substances has allowed to obtain a dermatological formulation having a suitable consistence, a proper heat stability and a satisfactory activity release in comparison with reference formulation.