Pelletization in Rotary Shaker Effect of Equipment Variables on Pelletization of Ferrous Fumarate

Abstract

A novel method and equipment viz. rotary shaker pelletizer has been developed for making spheres of pharmaceuticals. Essentially based on laboratory rotary shaker, the equipment variables that influence pelletization were determined using ferrous fumarate as the model drug and the results were used to optimize equipment design. Variables studied were orbital diameter of the rotary shaker, and diameter and texture of bottom surface of the bowl. The results indicate that the equipment is versatile in producing large quantities of ferrous fumarate pellets in short processing times and that a critical orbital diameter of the shaker and bowl size and roughness of the bottom surface of bowl, preferably with a raised conical bottom, is essential for best output.