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ORIGINAL ARTICLE

Prevalence, Supplementation, and Impact of Vitamin D Deficiency in Multiple Myeloma Patients

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Pages 505-509 | Received 28 May 2015, Accepted 06 Aug 2015, Published online: 27 Oct 2015
 

Abstract

Here, we studied 83 unselected multiple myeloma patients from December 2007 through December 2014. Lower 25(OH) D levels (<10 ng/mL) were associated with higher number of plasma cells in the bone marrow. Supplementation of vitamin D was accompanied with a significant increase in hemoglobin (11.8 to 12.3 p = .039), leukocyte (4.9 to 5.8 p = .011), and erythrocyte (3.8 to 4.0 p = .004) levels, while thrombocytes (200.5 to 175.2 p = .036) decreased. In conclusion, the present study found a high incidence of vitamin D deficiency and insufficiency in MM patients. In myeloma patients, vitamin D levels and supplementation should be more widely taken into account.

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