Lymphomas of T-Cell Phenotype

Abstract

Malignant lymphomas disrupt the anatomical organization of lymphoid organs and are recognized by patterns of growth and the morphology of the abnormal cells. The phenotype of these cells can be determined with precision by the demonstration of cell surface receptors and antigenic determinants by standard immunologic procedures. Most B-cells are found within discrete follicles and display characteristic cytologic and immunologic features. Although malignant proliferations of B-cells do not follow normal structural boundaries.