In Vivo Determination of ATP in Tumors Using ³¹P Inversion Spin Transfer

Luke J. Haseler School of Science, Griffith University, Nathan, 4111

Brian T. Bulliman Department of Biochemistry, Sydney University, Sydney, 2001

Phillip W. Kuchel Department of Biochemistry, Sydney University, Sydney, 2001

David M. Doddrell School of Science, Griffith University, Nathan, 4111

John R. Bell Department of Pathology, Mater Misericordiae Hospitals, South Brisbane, 4101, Australia

Michael G. Irving School of Science, Griffith University, Nathan, 4111

Abstract

The in vivo exchange kinetics of creatine kinase in the hind leg muscle of rats containing a transplanted mammary adenocarcinoma has been investigated using ³¹P magnetic resonance spectroscopy. Using a solenoid coil, the adenosine triphosphate (ATP) resonances arising from the tumor could be distinguished from ATP resonances arising from the muscle surrounding the tumor by use of inversion spin transfer techniques. This procedure affords a specific method of evaluating ATP metabolism of tumors in vivo.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

In Vivo Determination of ATP in Tumors Using ³¹P Inversion Spin Transfer

Information for

Open access

Opportunities

Help and information

In Vivo Determination of ATP in Tumors Using 31P Inversion Spin Transfer

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature

In Vivo Determination of ATP in Tumors Using ³¹P Inversion Spin Transfer