Semantics and the Chemotherapy of Hodgkin's Disease—Resistance is Not Relapse: Alternative Chemotherapy Lacks Effectiveness for Disease Not Totally Responsive to Initial MOPP Treatment

Morton Coleman Division of Hematology-Oncology, The New York Hospital-Cornell University Medical Center, New York, New York

Robert J. Friedlahder Division of Hematology-Oncology, The New York Hospital-Cornell University Medical Center, New York, New York

Abstract

Patients with advanced Hodgkin's disease not achieving a complete remission with initial MOPP therapy are significantly less responsive to adriamycin and nitrosourea-containing regimens than patients with relapsing disease following a complete remission with MOPP. Hodgkin's disease not responding completely to initial four-drug treatment represents resistant disease which, in most instances, may not be cured with existing alternative chemotherapy. These patients should receive innovative treatment.

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Semantics and the Chemotherapy of Hodgkin's Disease—Resistance is Not Relapse: Alternative Chemotherapy Lacks Effectiveness for Disease Not Totally Responsive to Initial MOPP Treatment

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Semantics and the Chemotherapy of Hodgkin's Disease—Resistance is Not Relapse: Alternative Chemotherapy Lacks Effectiveness for Disease Not Totally Responsive to Initial MOPP Treatment

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