Chemotherapy of Metastatic Merkel Cell Cancer

John Crown Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Roberto Lipzstein Radiation Oncology The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Seymour Cohen Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Michael Goldsmith Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Nathaniel Wisch Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

P. Alberto Paciucci Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Lewis Silverman Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Martin Weiner Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Ira Jaffrey Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

Larry Norton Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

James Holland Departments of Neoplastic Diseases, The Mount Sinai Medical Center, 1 Gustave L. Levy Place, New York, New York, 10029

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Abstract

Out of 16 cases of Merkel cell cancer identified in the records of the Mt. Sinai Medical Center or affiliates, 11 patients developed systemic metastases. Literature review confirms the substantial possibility of dissemination. Both in our series and in the literature, cytotoxic chemotherapy produced a high rate of usually short-lived response, although one of our patients with disseminated metastases achieved complete remission for two years.

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Chemotherapy of Metastatic Merkel Cell Cancer

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Chemotherapy of Metastatic Merkel Cell Cancer

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