ERRATUM

This article refers to:

Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression

Partonen T, Treutlein J, Alpman A, Frank J, Johansson C, Depner M, Aron L, Rietschel M, Wellek S, Soronen P, Paunio T, Koch A, Chen P, Lathrop M, Adolfsson R, Persson M-L, Kasper S, Schalling M, Peltonen L, Schumann G: Three circadian clock genes Per2, Arntl and Npas2 contribute to winter depression. Ann Med 2007;39:229–238.

It has come to our attention that the allele annotation for the rs2290035 polymorphisms was incorrectly listed in Tables I and III. The correct versions are reproduced below:

Table I. Minor allele frequencies.

		SNP				Minor allele frequency
Chromosome Number	Gene Name	Name	ID	Position	Alleles* Name	Controls	Patients
2	PER2	10870	10870	238967505	G (A)	0.11	0.16
2	PER2	10562	rs2304674	238963904	C (T)	0.31	0.34
2	PER2	10563	rs13033501	238963860	A (G)	0.12	0.1
2	PER2	10565	rs10201361	238955905	G (C)	0.01	0.02
2	NPAS2	Y353Y	rs1562313	101045973	A (G)	0.15	0.18
2	NPAS2	A394T	rs2305160	101049822	A (G)	0.38	0.33
2	NPAS2	S471L	S471L	101052708	A (G)	0.2	0.2
2	NPAS2	A640A	rs1053091	101065328	T (C)	0.04	0.05
11	ARNTL		rs2279287	13255061	A (G)	0.3	0.28
11	ARNTL		rs3789327	13341892	G (A)	0.42	0.48
11	ARNTL		rs969485	13359619	G (A)	0.25	0.24
11	ARNTL		rs2290035	13364347	T (A)	0.43	0.42

*Minor allele (major allele in parentheses).

Table III. Step-wise logistic regression analysis of the single-nucleotide polymorphisms.

						Odds ratio
Gene	Patients n	Controls n	Significance (model) P-value	SNP	Significance (effect) P-value	OR	95% CI
PER2	177	173	0.03	10870	0.03	1.66	1.06 – 2.60
ARNTL	137	136	0.01	rs2290035	0.02	–	–
				A/A vs. T/T	0.19	0.62	0.31 – 1.27
				A/T vs. A/A	0.09	1.60	0.93 – 2.74
NPAS2	159	159	0.004	S471L	0.02	–	–
				A/A vs. G/G	0.05	8.14	1.01 –65.48
				G/A vs. G/G	0.07	0.65	0.40 – 1.04