Age and Organ Dependent Variations in the Number of Thymus Derived Rtla Bearing Cells

S. Fujiwara Institute of Immunology, Department of Medicine, Medical Biophysics, Medical Genetics and Clinical Biochemistry, Toronto, Ontario, Canada, M5S 1A8; University of Toronto, Toronto, Ontario, Canada, M5S 1A8

R. M. Armstrong Institute of Immunology, Department of Medicine, Medical Biophysics, Medical Genetics and Clinical Biochemistry, Toronto, Ontario, Canada, M5S 1A8; University of Toronto, Toronto, Ontario, Canada, M5S 1A8

B. Cinader Institute of Immunology, Department of Medicine, Medical Biophysics, Medical Genetics and Clinical Biochemistry, Toronto, Ontario, Canada, M5S 1A8; University of Toronto, Toronto, Ontario, Canada, M5S 1A8

Abstract

The identification of a thymus antigen on rabbit cells has made it possible to determine the number and proportion of RTLA (rabbit thymus lymphocyte antigen) bearing thymus derived cells in various lymphoid tissues. In an earlier study, this has been measured by complement mediated cell kill. In this report, the proportion of thymus and bursa-equivalent cells was obtained by means of immunofluorescenf staining. The proportion of RTLA cells is in agreement with that found by cytotoxicity. Age dependent changes in the organ content of RTLA bearing and of Ig bearing cells are described.

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Age and Organ Dependent Variations in the Number of Thymus Derived Rtla Bearing Cells

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Age and Organ Dependent Variations in the Number of Thymus Derived Rtla Bearing Cells

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