Nwsm, A Mitogen from Nocardia Opaca, Specific for Rabbit Bursa Equivalent Cells (1)

C. Bona Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

L. Chedid Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

C. Damais Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

R. Ciorbaru Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

N. Shek Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

S. Dubiski Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

B. Cinader Institut Pasteur, C.N.R.S., Paris, Institut de Biochemie, Orsay, France; Institute of Immunology, University of Toronto, Canada, M5S 1A8

show all

Abstract

Treatment of rabbit spleen cells with a water soluble mitogen from Nocardia opaca (NWSM) resulted in the appearance of 30% of cells with the ultrastructural characteristics of plasmocytes and in enhanced thymidine uptake. The extent of incorporation was not diminished by prior complement mediated killing of thymus derived cells with a goat antibody, directed against rabbit thymus lymphocyte antigen (RTLA). The exposure of rabbit spleen cells to NWSM resulted in a polyclonal antibody response. It was concluded that NWSM is a potent mitogen for bursa equivalent lymphoid cells of the rabbit.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Nwsm, A Mitogen from Nocardia Opaca, Specific for Rabbit Bursa Equivalent Cells (1)

Information for

Open access

Opportunities

Help and information

Nwsm, A Mitogen from Nocardia Opaca, Specific for Rabbit Bursa Equivalent Cells (1)

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature