Selective Transport of an Oligomeric Iga Into Canine Saliva

Abstract

Evidence is presented which shows that an oligomeric IgA myeloma protein, possessing J-chain but lacking secretory component, is selectively transferred from serum into canine saliva. The data also demonstrate that ¹²⁵l-label remains with the IgA during the transfer process. These data interpreted in the light of findings in humans support the concept that the oligomeric form of IgA, devoid of secretory component, is required to achieve selective transport.