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Immunological Communications Volume 13, 1984 - Issue 5
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Original Article

Reactions of Infectious Mononucleosis Sera with Glutaraldehyde-Treated Human Erythrocytes

M. Wasik Department of Microbiology, School of Medicine, State University of New York at Buffalo, Buffalo, New York, 14214
&
F. Milgrom Department of Microbiology, School of Medicine, State University of New York at Buffalo, Buffalo, New York, 14214
Pages 439-445 | Published online: 07 Jul 2009
 
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Abstract

Infectious mononucleosis sera gave positive results in enzymoimmunoassay with glutaraldehyde-treated human erythrocytes. This unexpected reaction appeared to be caused by the interaction of Paul-Bunnell (P-B) antibodies with a partial P-B antigen that apparently appears on human red blood cells in a hidden form and becomes exposed by the treatment with glutaraldehyde.

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