Cytochemical Characterization of Mouse L1210 Leukemia

J. Kawiak Department of Cytophysiology, Medical Center of Postgraduate Education, 01–813, Warsaw, Poland

T. Skorski Department of Cytophysiology, Medical Center of Postgraduate Education, 01–813, Warsaw, Poland

A. Ciechanowicz Department of Histology and Embryology, Pomeranian Academy of Medicine, 70–111, Szczecin, Poland

M. Zylińska Department of Histology and Embryology, Pomeranian Academy of Medicine, 70–111, Szczecin, Poland

H. J. Seidel Department of Clinical Physiology and Occupational Medicine, University of Ulm, Oberer Eselsberg, 7900, Ulm, Federal Republic of Germany

M. Kawalec Department of Cytophysiology, Medical Center of Postgraduate Education, 01–813, Warsaw, Poland

B. Gnatowski Centre for Radiation and Radioprotection, Military Medical School, 00–909, Warsaw, Poland

A. Czarnomska Department of Tumor Biology, Oncological Centre – M. Sklodowska-Curie Institute, 00–973, Warsaw, Poland

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Abstract

Mouse lymphatic leukemia L1210 cells were characterized with polyclonal and monoclonal antibodies and lectins. The cells were found to have the phenotype IgG^-, Thy-1.2^-, Lyt-1^-, Lyt-2^-, asialo-GM^-, TL^-, I-A^d-, IL-2R⁺, peanut agglutinin⁺, and Helix pomatia lectin +/-. They retained expression of H-2K^d and H-2D^d. Thus, these cells resemble “null” cells.

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Cytochemical Characterization of Mouse L1210 Leukemia

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Cytochemical Characterization of Mouse L1210 Leukemia

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