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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 24, 1995 - Issue 1-2
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Original Article

Transfusion Strategies: Opportunities for Improvement

Pages 423-430 | Published online: 07 Jul 2009
 

Abstract

Opportunities for improving transfusion practice that involve patient care, technological advancements, and technology changes in the clinical arena are discussed. Patient care should be enhanced by optimizing transfusion therapy and the source of donors of platelet concentrates, i.e., single donor platelets (obtained by plateletapheresis from a single donor) or to random donor platelets (containing a pool of six to eight platelet concentrates separated from whole blood donations). The availability of third-generation'' leukocyte-reduction filters provides the technology for significantly and consistently providing leukocyte reduced blood components. The potential benefits of using these filters is presented. Platelet crossmatching represents a technology change involving clinical practice. Suggestions for incorporating this test into platelet transfusion algorithms are included.

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