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Research Article

The Genetics of Keratoconus

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Pages 275-280 | Received 16 Jun 2013, Accepted 11 Jul 2013, Published online: 18 Oct 2013
 

Abstract

Keratoconus is a bilateral, non-inflammatory corneal ectasia characterized by progressive conical thinning and protrusion of the cornea. Its etiology has long been believed to be multifactorial, with environmental, behavioral, and genetic factors all contributing to the disease process. This review focuses specifically on examining the evidence that supports a genetic basis for keratoconus.

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