The recent emerging of novel Middle East respiratory syndrome is an important concern in global public health.Citation1 This new infection has its clinical feature similar to SARS but with additional non-respiratory symptoms.Citation1 This infection is proved as a zoonosis caused by cross species coronavirus with its primary origin in wild bats.Citation2 From its first identification in 2012, there are around 70 confirmed infected cases with more than half ended up with death.Citation1 Focusing on atypical clinical presentations of novel Middle East respiratory syndrome, the renal failure is an important presentation.Citation1,Citation3 In almost all death cases, acute renal failure can be identified.Citation1,Citation3,Citation4 Focusing on the course, the patients usually starts with acute febrile illness with rapid progression to severe respiratory distress syndrome then acute renal failure occurs on top.Citation1,Citation3,Citation4 This nature is a significant difference from the already known SARS, of which, no predominant renal failure can be observed. The underlying cause of acute renal failure in novel Middle East respiratory syndrome is still the myth. Whether this new virus also has the target site at renal tissue in additional to respiratory tract epithelium is the question to be further studied. The scientific evidence that support the possibility that the virus might have additional target site at kidney is the confirmation of in vitro growth of virus in renal cell culture.Citation5
References
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