Abstract
A 12-year-old girl with disseminated immunoblastic sarcoma, a rare tumor in childhood, was treated with the Pediatric Oncology Group (POG) protocol for non-Hodgkin's lymphoma (POG #7905) using (1) vincristine, prednisone, adriamycin, cyclophosphamide, (2) cranial radiation and intrathecal methotrexate and hydrocortisone for central nervous system prophylaxis, (3) rotating agent pulse therapy of adriamycin, vincristine cyclophosphamide, 6-mer-captopurine and methotrexate for maintenance. No bulk disease was present at exploratory laparotomy done at the end of induction, although microscopic tumor was present. No radiation to abdomen or thorax was given. Treatment was stopped three years after diagnosis. Two years and nine months later she is disease-free and presumed cured.
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