Mhc Gene Products and Anticardiolipin Antibodies in Systemic Lupus Erythematosus Results of a Multicenter Study

K. Hartung Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Germany

R. Coldewey Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Germany

A. Corvetta Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Ancona, Italy

H. Deicher Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Germany

J. R. Kalden Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Erlangen, Germany

F. Krapf Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Erlangen, Germany

B. Lang Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Freiburg, Germany

H. J. Lakomek Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Düsseldorf, Germany

B. Liedvogel ELIAS-Medizintechnik GmbH, Freiburg, FRG

H. H. Peter Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Freiburg, Germany

D. Schendel Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, München, Germany

Ch. Specker Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Düsseldorf, Germany

W. Stangel Departments of Medicine and Immunology and Bloodbank, Universities of Hannover, Germany

show all

Abstract

Anticardiolipin antibodies (aCL) and HLA-DR antigens were determined in 314 central European patients with systemic lupus erythematosus (SLE). Both HLA-DR4 and DR7 were increased in aCL-positive patients, and aCL were significantly associated with DRw53.

The association between DRw53 and aCL was also apparent in those 17 patients with SLE and the anticardiolipin syndrome. There was no association between aCL and HLA-DQ or C4 alleles in SLE.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Mhc Gene Products and Anticardiolipin Antibodies in Systemic Lupus Erythematosus Results of a Multicenter Study

Information for

Open access

Opportunities

Help and information

Mhc Gene Products and Anticardiolipin Antibodies in Systemic Lupus Erythematosus Results of a Multicenter Study

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature