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Research Article

Enhancement of Immune Response of Murine Peyer's Patches by a Diet Supplemented With Yogurt

, , , , , & show all
Pages 87-100 | Published online: 28 Sep 2008
 

Abstract

The first line of defense against pathogens that enter the host by the oral route involves the Peyer's Patches (PP). For centuries many populations of the mediterranean basin have empirically administered soured milk (yogurt. to prevent and treat diarrhoea and entero-colitis. Recent reports have offered evidence in favour of a possible influence of yogurt on the host's immunocompetence.

Scope of the present study was to evaluate the influence of a diet supplemented with yogurt on the PP from BALB/c mice.

The results reported here suggest that yogurt feeding potentiates the host's cell-mediated immune response by increasing the percentage of B lymphocytes and the PHA and LPS-induced proliferative responses of PP cell suspensions.

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