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Immunopharmacology and Immunotoxicology Volume 15, 1993 - Issue 2-3
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Research Article

Effects of Acetate on Human Immune System

Shigeaki Ishizaka Third Department of Internal Medicine, Nara Medical University, Kashihara, Nara, 634, Japan
,
Eiryo Kikuchi Third Department of Internal Medicine, Nara Medical University, Kashihara, Nara, 634, Japan
&
Tadasu Tsujii Third Department of Internal Medicine, Nara Medical University, Kashihara, Nara, 634, Japan
Pages 151-162 | Published online: 28 Sep 2008
 
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Abstract

The immunopharmacologic effects of Ringer's acetate on healthy persons and cancer patients were investigated. Enhancement of in vivo polyclonal antibody production in peripheral blood lymphocytes from healthy subjects and cancer patients was elicited after the intravenous administration of 500 ml Ringer's acetate solution. Allogeneic mixed lymphocyte reaction (MLR) and natural killer (NK) activity were also increased in the majority of healthy individuals and cancer patients when administered Ringer's acetate solution but not Ringer's lactate solution.

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