Blood Sample Analysis and Monitoring of Hemodynamic Parameters and Renal Function in the Conscious Rat

M. Hohenfellner Department of Physiology, University of Munich, Pettenkoferstraβ128, München, 2, Germany

U. Schmausser Department of Physiology, University of Munich, Pettenkoferstraβ128, München, 2, Germany

H. G. Klein Department of Physiology, University of Munich, Pettenkoferstraβ128, München, 2, Germany

H. Brechtelsbauer Department of Physiology, University of Munich, Pettenkoferstraβ128, München, 2, Germany

Abstract

A method is described for chronic instrumentation of the rat with arterial and venous catheters. The technique minimizes the risk of catheter occlusion and damage, and reduces restraint of the animals during the evaluation. In the conscious animal, hemodynamic parameters and renal function can be monitored while substances are injected or blood samples withdrawn.

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Blood Sample Analysis and Monitoring of Hemodynamic Parameters and Renal Function in the Conscious Rat

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Blood Sample Analysis and Monitoring of Hemodynamic Parameters and Renal Function in the Conscious Rat

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