![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
A method for testing the sterility of large, gentamicin-containing, egg phosphatidylcholine (EPC) liposome suspensions is described. The method consists of diluting the liposome formulation in four volumes of 1.5% triton X-100 (final EPC concentration in the detergent solution is approximately 10 mg/ml) and then filtering the cloudy suspension as outlined by the USP for the membrane filtration sterility test. The method was not bacteriocidal or fungicidal for the organisms tested.