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Original Article

Persistent Intermediate Uveitis Associated with Latent Manifestation of Facial Large B-Cell Non-Hodgkin Lymphoma

E. Jason Sabet-PeymanWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; and Doheny Eye Institute, University of Southern California, Los Angeles, California, USA

, BA, MD,

Charles G. EberhartWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; and Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

, MD,

Kashif JanjuaWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

, MD,

Syed Mahmood ShahWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

, MBBS,

Diana V. DoWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

, MD &

Quan Dong NguyenWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USACorrespondence[email protected]

, MD, MSc

Abstract

Purpose: To report a case of intraocular non-Hodgkin lymphoma (NHL) manifesting as persistent intermediate uveitis, facial mass, and Bell palsy.

Design: Retrospective, interventional case report.

Methods: A 51-year-old patient with persistent intermediate uveitis for 4 years is diagnosed with intraocular NHL after developing Bell palsy and a facial mass. Initial diagnostic vitrectomy was inconclusive.

Results: Subsequent treatment with cyclophosphamide, adriamycin, vincristine, prednisone, and rituximab resulted in regressed facial mass and improved visual acuity.

Conclusion: NHL can manifest as latent Bell palsy and facial mass in addition to the more common symptoms of uveitis. Intraocular NHL should be suspected in any patient of any age with persistent uveitis.

KEYWORDS::

ACKNOWLEDGMENTS

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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Persistent Intermediate Uveitis Associated with Latent Manifestation of Facial Large B-Cell Non-Hodgkin Lymphoma

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Persistent Intermediate Uveitis Associated with Latent Manifestation of Facial Large B-Cell Non-Hodgkin Lymphoma

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ACKNOWLEDGMENTS

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