A Case of Corneal Endotheliitis with Mumps Virus RNA in Aqueous Humor Detected by RT-PCR

Abstract

Purpose: To report a case of corneal endotheliitis following the mumps parotitis.

Methods: A 46-year-old man noticed ciliary infection and visual loss in the right eye after mumps parotitis. To determine the cause of the disease, reverse transcription–polymerase chain reaction (RT-PCR) was used to amplify mumps virus RNA in samples from the aqueous humor.

Results: RT-PCR revealed mumps virus RNA in an aqueous humor sample. Although full recovery of vision was achieved within 1 month of the onset, corneal endothelial cells were severely damaged.

Conclusions: The authors have detected mumps virus in the aqueous humor by RT-PCR for the first time.

• Corneal endotheliitis
• mumps virus RNA