Choroidal Thickness in Ocular Sarcoidosis during Quiescent Phase Using Enhanced Depth Imaging Optical Coherence Tomography

Abstract

Purpose: To evaluate the choroidal thickness in patients with ocular sarcoidosis during quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing it with normal subjects.

Method: Eighteen eyes of 9 patients with ocular sarcoidosis (8 women, 1 man, mean age: 59.12 ± 18.49 years) were enrolled in this study. Their subfoveal choroidal thickness was measured using EDI-OCT in the quiescent phase of uveitis, and compared with the age-, sex-, and spherical equivalent-matched normal subjects (6 women, 3 men, mean age: 59.6 ± 14.22 years).

Results: The mean subfoveal choroidal thickness was 281.76 ± 88.1 µm in patients with sarcoidosis and 342.32 ± 71.02 µm in controls. Significant differences were found at points between nasal 1500 µm and temporal 1000 µm to the fovea between patients and control group (p = 0.002, at fovea).

Conclusions: Patients with ocular sarcoidosis had thinner choroids in the quiescent phases when compared to normal subjects.

• Choroidal thickness
• enhanced depth imaging optical coherence tomography
• quiescent phase
• sarcoidosis
• uveitis