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Original Articles

Macular Changes Correlate with the Degree of Acute Anterior Uveitis in Patients with Spondyloarthropathy

, PhD, , PhD & , DSc
Pages 153-158 | Received 27 Apr 2014, Accepted 15 Jul 2014, Published online: 20 Aug 2014
 

Abstract

Purpose: To evaluate the correlation between anterior chamber inflammation and the central foveal thickness of the retina in a homogenous uveitic group (seronegative spondyloarthropathy (subgroup: ankylosing spondylitis)) of patients with the first acute anterior unilateral uveitic attack.

Methods: Central foveal thickness (FT) and perifoveal retinal thickness were recorded by optical coherence tomography (Optovue RTVue-100), and the difference between the two eyes was calculated. Statistical analysis was performed by Mathworks Matlab software. Anterior chamber inflammation was measured by laser flare photometry (Kowa FM-600).

Results: A statistically significant (p < .05) increase was found in retinal thickness in all OCT subfields in acute anterior uveitic eyes compared to healthy fellow eyes. There was a linear correlation between the degree of inflammation (laser flare photometry values) and central foveal thickness (r = .900, p < .001).

Conclusions: We could demonstrate close correlation between macular thickness and inflammation in anterior uveitic patients with spondyloarthropathy.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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