Discrepancy in Fluorescein Angiography and Optical Coherence Tomography Findings of Macular Edema in Intermediate Uveitis

ABSTRACT

Purpose: To assess discrepancies between fluorescein angiography (FA) and optical coherence tomography (OCT) findings for macular edema (ME) in intermediate uveitis, and investigate treatment response differences corresponding to the discrepant patterns.

Methods: Discrepant results for ME detection between FA and OCT were evaluated. After 6 months, differences in treatment responses were analyzed.

Results: Discrepant findings for ME were found in 21 (44%) of 48 eyes. The best-corrected visual acuity significantly improved after treatment in the concordant group but not in the discrepant groups. Central retinal thickness significantly decreased after treatment in the FA+/OCT+ and FA−/OCT+ groups but not in the FA+/OCT− group. Disease duration was significantly longer in the FA+/OCT− group than in the other groups.

Conclusions: Discrepancies in FA and OCT findings for ME were common in patients with intermediate uveitis. Our results suggest that treatment outcomes may differ according to the discrepant patterns.

Keywords:

• Discrepancy
• fluorescein angiography
• intermediate uveitis
• macular edema
• optical coherence tomography

ACKNOWLEDGMENT

B. H. Kim and J. Y. Shin equally contributed to this work as co-first authors.

DECLARATION OF INTEREST

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.

FUNDING

This research was supported by a grant (12172MFDS231) from the Korean Ministry of Food and Drug Safety in 2012.

Additional information

Funding

This research was supported by a grant (12172MFDS231) from the Korean Ministry of Food and Drug Safety in 2012.