Evolving “Diagnostic” Criteria for Axial Spondyloarthritis in the Context of Anterior Uveitis

ABSTRACT

Anterior uveitis is far more common than intermediate, posterior or panuveitis. About 50% of patients with acute anterior uveitis are HLA B27+. Those who are HLA B27+ are highly likely to have associated back, joint, or tendon disease. The majority of patients with acute anterior uveitis and inflammatory low back pain are suffering from axial spondyloarthritis and radiographic evidence for abnormal sacroiliac joints is not required to make this diagnosis.

Received 12 October 2015; revised 31 January 2016; accepted 16 February 2016; published online 12 April 2016

Keywords:

• Acute anterior uveitis
• ankylosing spondylitis
• axial spondyloarthritis
• HLA B27
• spondyloarthropathy

DECLARATION OF INTEREST

The author has consulted for or received grant support from Janssen, UCB, Abbvie, Allergan, and Alcon

FUNDING

The author received financial support from the Spondylitis Association of America, the Stan and Madelle Rosenfeld Family Trust, the William and Mary Bauman Foundation, Research to Prevent Blindness New York, and grants from the National Institutes of Health, P30EY010572 and RO1 EY021733.

Additional information

Funding

The author received financial support from the Spondylitis Association of America, the Stan and Madelle Rosenfeld Family Trust, the William and Mary Bauman Foundation, Research to Prevent Blindness New York, and grants from the National Institutes of Health, P30EY010572 and RO1 EY021733.